Gper1^tm1135.2Arte
Targeted Allele Detail

Summary

• Symbol: Gper1^tm1135.2Arte
• Name: G protein-coupled estrogen receptor 1; targeted mutation 1135.2, TaconicArtemis
• MGI ID: MGI:3839350
• Gene: Gper1 Location: Chr5:139408906-139413555 bp, + strand Genetic Position: Chr5, 78.58 cM, cytoband G1
• Alliance: Gper1^tm1135.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145794
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exon 3 and the neo cassette. The absence of transcript expression was confirmed by quantitative RT-PCR on stomach, ovary, mammary gland, and uterus extracts. (J:145794)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gper1 Mutation: 30 strains or lines available

References

• Original: J:145794 Otto C, et al., GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol Reprod. 2009 Jan;80(1):34-41
• All: 2 reference(s)