Tg(Pdx1-cre/Esr1*)1Mga
Transgene Detail

Summary

• Symbol: Tg(Pdx1-cre/Esr1*)1Mga
• Name: transgene insertion 1, Maureen A Gannon
• MGI ID: MGI:3839433
• Synonyms: Pdx1^AI-III-Cre/ERT, pdx1^PBCreER^TM, Tg(Pdx1-cre/ERT)1Mga
• Transgene: Tg(Pdx1-cre/Esr1*)1Mga Location: unknown
• Alliance: Tg(Pdx1-cre/Esr1*)1Mga page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Pdx1-cre/Esr1*)1Mga expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pdx1

• Mutation details: The 1 kb islet enhancer was used to drive inducible islet-specific expression of a cre/Esr1 fusion. Three lines were created with line 1 exhibiting the strongest expression. (J:99581)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1. Comparative matrix view of recombinase activities

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pdx1-cre/Esr1*)1Mga

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:99581 Zhang H, et al., Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase. Genesis. 2005 Jul;42(3):210-7
• All: 33 reference(s)