Klf13^tm1Kren
Targeted Allele Detail

Summary

• Symbol: Klf13^tm1Kren
• Name: Kruppel-like transcription factor 13; targeted mutation 1, Alan M Krensky
• MGI ID: MGI:3839530
• Gene: Klf13 Location: Chr7:63536099-63588663 bp, - strand Genetic Position: Chr7, 34.58 cM
• Alliance: Klf13^tm1Kren page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145839
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neomycin selection cassette. PCR analysis could not detect any mRNA in homozygous mice and Western blot analysis did not detect any protein in either thymocytes or splenocytes. (J:145839)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf13 Mutation: 47 strains or lines available

References

• Original: J:145839 Zhou M, et al., Kruppel-like transcription factor 13 regulates T lymphocyte survival in vivo. J Immunol. 2007 May 1;178(9):5496-504
• All: 6 reference(s)