Tg(CD74*)1Ayr
Transgene Detail

Summary

• Symbol: Tg(CD74*)1Ayr
• Name: transgene insertion 1, Alexander Y Rudensky
• MGI ID: MGI:3839582
• Synonyms: hIi^BAD-CLIP
• Transgene: Tg(CD74*)1Ayr Location: unknown
• Alliance: Tg(CD74*)1Ayr page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1 x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD74*)1Ayr expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD74 (972)

  Cd74	(MGI:96534)

• Mutation details: The human form of the gene contains 4 amino acid substitutions in the CLIP domain. Seven lines were created but no names/numbers were assigned. (J:88717)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:88717 Honey K, et al., Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M. J Immunol. 2004 Apr 1;172(7):4142-50
• All: 1 reference(s)