Tg(ACTA1-Capn3*)27.10Spc
Transgene Detail

Summary

• Symbol: Tg(ACTA1-Capn3*)27.10Spc
• Name: transgene insertion 27.10, Melissa J Spencer
• MGI ID: MGI:3839617
• Transgene: Tg(ACTA1-Capn3*)27.10Spc Location: unknown
• Alliance: Tg(ACTA1-Capn3*)27.10Spc page

Transgene origin

• Strain of Origin: (C57BL/6J x BALB/c)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA1-Capn3*)27.10Spc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Capn3 (MGI:107437)

• Mutation details: A construct with the human skeletal alpha actin promoter driving the mouse calpain 3 sequence lacking exon 6, thereby removing the IS1 domain, was microinjected into (C57BL/6J x BALB/c)F2 oocytes and integrated via random insertion. (J:77348)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:77348 Spencer MJ, et al., Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8874-9
• All: 1 reference(s)