Tg(Akr1b7-cre)1Anm
Transgene Detail

Summary

• Symbol: Tg(Akr1b7-cre)1Anm
• Name: transgene insertion 1, Antoine Martinez
• MGI ID: MGI:3839676
• Synonyms: 0.5 akr1b7-cre
• Transgene: Tg(Akr1b7-cre)1Anm Location: unknown
• Alliance: Tg(Akr1b7-cre)1Anm page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Akr1b7-cre)1Anm expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Akr1b7 (MGI:101918)

• Mutation details: This transgene consists of a 0.5 kb fragment of the of the 5' flanking sequence of the murine Akr1b7 gene, the coding region and 3' untranslated region of the cre gene, a metallothionein I poly a signal, and a 3.5 kb intragenic fragment spanning intron 1 to intron 2 of the mouse Akr1b7 gene. Cre activity was detected in the adrenal cortex and kidney but not in the gonads or vas deferens. (J:146966)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Akr1b7 (mouse) Summary of all recombinase alleles driven by Akr1b7. Comparative matrix view of recombinase activities Alliance mouse Akr1b7 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:146966 Lambert-Langlais S, et al., A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex. Mol Cell Endocrinol. 2009 Mar 5;300(1-2):197-204
• All: 13 reference(s)