Lypd1^tm1.1Tmj
Targeted Allele Detail

Summary

• Symbol: Lypd1^tm1.1Tmj
• Name: Ly6/Plaur domain containing 1; targeted mutation 1.1, Thomas M Jessell
• MGI ID: MGI:3840549
• Synonyms: Lynx2^-
• Gene: Lypd1 Location: Chr1:125795359-125840838 bp, - strand Genetic Position: Chr1, 54.7 cM
• Alliance: Lypd1^tm1.1Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146775
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exons 1 and 2 were removed by germ line, cre mediated recombination. The absence of transcript expression was confirmed by in situ hybridization on brain sections. (J:146775)

Generation of the Lypd1^tm1Tmj and Lypd1^tm1.1Tmj alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lypd1 Mutation: 14 strains or lines available

References

• Original: J:146775 Tekinay AB, et al., A role for LYNX2 in anxiety-related behavior. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4477-82
• All: 1 reference(s)