Dscam^tm1.1Kzy
Targeted Allele Detail

Summary

• Symbol: Dscam^tm1.1Kzy
• Name: DS cell adhesion molecule; targeted mutation 1.1, Kazuhiro Yamakawa
• MGI ID: MGI:3840666
• Gene: Dscam Location: Chr16:96392040-96971952 bp, - strand Genetic Position: Chr16, 57.02 cM, cytoband C
• Alliance: Dscam^tm1.1Kzy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146754
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exon 1. The absence of transcript expression was confirmed by RT-PCR on brain extracts. (J:146754)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dscam Mutation: 106 strains or lines available

References

• Original: J:146754 Amano K, et al., DSCAM deficiency causes loss of pre-inspiratory neuron synchroneity and perinatal death. J Neurosci. 2009 Mar 4;29(9):2984-96
• All: 5 reference(s)