Hoxd13^tm2Ddu
Targeted Allele Detail

Summary

• Symbol: Hoxd13^tm2Ddu
• Name: homeobox D13; targeted mutation 2, Denis Duboule
• MGI ID: MGI:3840811
• Synonyms: HoxD^(12-13)lac
• Gene: Hoxd13 Location: Chr2:74498654-74501943 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd13^tm2Ddu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:47366
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ with a 3' floxed neo cassette was inserted into exon 1. The neo cassette was subsequently removed by cre mediated recombination leaving a single loxP site. The ES cells used to create this allele contained Hoxd12^tm2Ddu and the insertions were selected for in cis. (J:47366)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd13 Mutation: 24 strains or lines available

References

• Original: J:47366 Kondo T, et al., Control of colinearity in AbdB genes of the mouse HoxD complex. Mol Cell. 1998 Jan;1(2):289-300
• All: 1 reference(s)