Del(2Cd44-Hoxd11)43Ddu
Targeted Allele Detail

Summary

• Symbol: Del(2Cd44-Hoxd11)43Ddu
• Name: deletion, Chr 2, Denis Duboule 43
• MGI ID: MGI:3840894
• Synonyms: Del43Ddu
• Gene: Del(2Cd44-Hoxd11)43Ddu Location: Chr2:74509902-102732010 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100298
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/Sv or 129S2/SvPas or 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(2Cd44-Hoxd11)43Ddu involves 706 genes/genome features (Olfr1190-ps1, A130042O14Rik, Olfr1072-ps1 ...) View all
• Mutation details: A sequential targeted recombination-induced genomic (STRING) approach using Cd44^tm2Ugu and Hoxd11^tm2.1Ddu produced an 11 cM deletion spanning Cd44 through Hoxd11. (J:100298)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Cd44-Hoxd11)43Ddu Mutation: 0 strains or lines available

References

• Original: J:100298 Spitz F, et al., Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet. 2005 Aug;37(8):889-93
• All: 1 reference(s)