Tg(Prrx1-Sox9,-lacZ)1Haak
Transgene Detail

Summary

• Symbol: Tg(Prrx1-Sox9,-lacZ)1Haak
• Name: transgene insertion 1, Haruhiko Akiyama
• MGI ID: MGI:3840957
• Synonyms: Prx1-Sox9/LacZ
• Transgene: Tg(Prrx1-Sox9,-lacZ)1Haak Location: unknown
• Alliance: Tg(Prrx1-Sox9,-lacZ)1Haak page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prrx1-Sox9,-lacZ)1Haak expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sox9 (MGI:98371)

• Mutation details: This transgene consists of a 2.4 kg fragment of the Prrx1 limb specific promoter driving expression of a 3x hemagglutinin tagged Sox9 cDNA followed by an IRES lacZ cassette. LacZ expression is seen in the limb buds starting at E9.5. (J:121946)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:121946 Akiyama H, et al., Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol. 2007 May;26(4):224-33
• All: 2 reference(s)