Ifnar2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ifnar2^m1Btlr
• Name: interferon (alpha and beta) receptor 2; mutation 1, Bruce Beutler
• MGI ID: MGI:3841008
• Synonyms: macro-2
• Gene: Ifnar2 Location: Chr16:91169671-91202477 bp, + strand Genetic Position: Chr16, 52.82 cM
• Alliance: Ifnar2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation was identified in an ex vivo screen of macrophages from G3 progeny of ENU mutagenized male mice for their ability to control viral infection. It comprises an A to T transition in the second of nine exons, which is the first coding exon of the gene, converting the methionine/translation initiation codon at nucleotide position 221 of the cDNA sequence to a codon specifying valine. (J:147329)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ifnar2 Mutation: 42 strains or lines available

References

• Original: J:147329 Won S, et al., Record for "macro-2", updated April 14th, 2009. MGI Direct Data Submission. 2009
• All: 2 reference(s)