Prima1^tm1Vebe
Targeted Allele Detail

Summary

• Symbol: Prima1^tm1Vebe
• Name: proline rich membrane anchor 1; targeted mutation 1, Veronique Bernard
• MGI ID: MGI:3841111
• Gene: Prima1 Location: Chr12:103163167-103208409 bp, - strand Genetic Position: Chr12, 52.9 cM, cytoband F1
• Alliance: Prima1^tm1Vebe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147425
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 3, which contains the PRAD domain, was replaced with a floxed neo cassette. (J:147425)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prima1 Mutation: 13 strains or lines available

References

• Original: J:147425 Dobbertin A, et al., Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-rich membrane anchor subunit and the attachment domain on the catalytic subunit. J Neurosci. 2009 Apr 8;29(14):4519-30
• All: 8 reference(s)