Tg(Prph1-cre)35Dmd
Transgene Detail

Summary

• Symbol: Tg(Prph1-cre)35Dmd
• Name: transgene insertion 35, David M Donovan
• MGI ID: MGI:3841120
• Synonyms: PCRE35, Per-cre
• Transgene: Tg(Prph1-cre)35Dmd Location: unknown
• Alliance: Tg(Prph1-cre)35Dmd page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prph1-cre)35Dmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Prph1

• Mutation details: Sequence encoding cre recombinase was adjoined to 5.8 kb of the peripherin 1 promoter region. In addition, a polyadenylation signal and peripherin 1 genomic sequence encompassing a portion of exon 1 through a portion of exon 3 was included downstream of cre. Transgenic expression was demonstrated in the dorsal root and trigeminal ganglia, the olfactory epithelium, and brainstem nuclei at E13. In addition, this is the only line reported for this construct that demonstrates sympathetic chain expression. (J:80936)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prph1 (species not specified) Summary of all recombinase alleles driven by Prph1.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:80936 Zhou L, et al., Murine peripherin gene sequences direct Cre recombinase expression to peripheral neurons in transgenic mice. FEBS Lett. 2002 Jul 17;523(1-3):68-72
• All: 3 reference(s)