Ar^tm1Rax
Targeted Allele Detail

Summary

• Symbol: Ar^tm1Rax
• Name: androgen receptor; targeted mutation 1, Richard Axel
• MGI ID: MGI:3841391
• Synonyms: Ar^{IRES-PLAP-IRES-nLacZ}
• Gene: Ar Location: ChrX:97192375-97366821 bp, + strand Genetic Position: ChrX, 42.82 cM
• Alliance: Ar^tm1Rax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147485
• Parent Cell Line: MM13 (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A cassette containing an IRES, a human ALPP, a second IRES, and a lacZ with a nuclear localization sequence was inserted along with a "self-excising" neomycin selection cassette 3 bp after the stop codon. (J:147485)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ar Mutation: 23 strains or lines available

References

• Original: J:147485 Shah NM, et al., Visualizing sexual dimorphism in the brain. Neuron. 2004 Aug 5;43(3):313-9
• All: 3 reference(s)