Olig3^tm1(cre)Ynka
Targeted Allele Detail

Summary

• Symbol: Olig3^tm1(cre)Ynka
• Name: oligodendrocyte transcription factor 3; targeted mutation 1, Yasushi Nakagawa
• MGI ID: MGI:3841452
• Synonyms: Olig^Cre
• Gene: Olig3 Location: Chr10:19232287-19234352 bp, + strand Genetic Position: Chr10, 8.33 cM
• Alliance: Olig3^tm1(cre)Ynka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147427
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Olig3^tm1(cre)Ynka expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Olig3 (MGI:2149955)

• Mutation details: was employed to replace the entire coding region of Olig3 was replaced via homologous recombination in ES cells using a targeting vector containing a cassette encoding Cre recombinase followed by a frt-Neo-frt (FNF) sequence. (J:147427)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Olig3 (mouse) Summary of all recombinase alleles driven by Olig3. Alliance mouse Olig3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olig3 Mutation: 9 strains or lines available

References

• Original: J:147427 Vue TY, et al., Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97
• All: 18 reference(s)