Tg(Fzd10-cre/Esr1*)1Chzh
Transgene Detail

Summary

• Symbol: Tg(Fzd10-cre/Esr1*)1Chzh
• Name: transgene insertion 1, Chunjie Zhao
• MGI ID: MGI:3841575
• Synonyms: Frizzled10-CreER^TM, Tg(Fzd10-cre/ERT2)1Chzh
• Transgene: Tg(Fzd10-cre/Esr1*)1Chzh Location: unknown
• Alliance: Tg(Fzd10-cre/Esr1*)1Chzh page

Transgene origin

• Strain of Origin: C57BL/6 x FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Fzd10-cre/Esr1*)1Chzh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fzd10 (MGI:2136761)

• Mutation details: The transgenic construct contained a 6.7 kb fragment upstream of the transcriptional start site of the mouse Fzd10 gene followed by a CreER^TM cassette carrying a polyA sequence. This construct was injected into fertilized oocytes with five transgenic founders obtained. Expression analysis showed that 3 lines exhibited expression patterns similar to a previously characterized transgenic Fzd10 reporter mouse line. One line was picked for further characterization. (J:146827)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fzd10 (mouse) Summary of all recombinase alleles driven by Fzd10. Comparative matrix view of recombinase activities Alliance mouse Fzd10 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:146827 Gu X, et al., Characterization of the Frizzled10-CreER transgenic mouse: an inducible Cre line for the study of Cajal-Retzius cell development. Genesis. 2009 Mar;47(3):210-6
• All: 4 reference(s)