Bnip3l^tm1Gwd
Targeted Allele Detail

Summary

• Symbol: Bnip3l^tm1Gwd
• Name: BCL2/adenovirus E1B interacting protein 3-like; targeted mutation 1, Gerald W Dorn
• MGI ID: MGI:3841600
• Synonyms: Nix^f
• Gene: Bnip3l Location: Chr14:67222688-67246326 bp, - strand Genetic Position: Chr14, 34.6 cM
• Alliance: Bnip3l^tm1Gwd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141583
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and an frt flanked neo resistance cassette were inserted in intron 3. At the same time, an additional loxP site was inserted in intron 6a. (J:141583)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bnip3l Mutation: 41 strains or lines available

References

• Original: J:141583 Diwan A, et al., Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6794-9
• All: 5 reference(s)