Use1^tm1Aha
Targeted Allele Detail

Summary

• Symbol: Use1^tm1Aha
• Name: unconventional SNARE in the ER 1 homolog (S. cerevisiae); targeted mutation 1, Akihiro Harada
• MGI ID: MGI:3842567
• Synonyms: p31^geo
• Gene: Use1 Location: Chr8:71819492-71822376 bp, + strand Genetic Position: Chr8, 34.43 cM, cytoband C1
• Alliance: Use1^tm1Aha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147771
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site followed by a Frt flanked cassette containing an splice acceptor, IRES, betageo, and polyA sequence were inserted into intron 4 and a second loxP site was inserted after exon 8 via homologous recombination. (J:147771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Use1 Mutation: 18 strains or lines available

References

• Original: J:147771 Uemura T, et al., p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival. Mol Cell Biol. 2009 Apr;29(7):1869-81
• All: 1 reference(s)