Btla^tm1Dgra
Targeted Allele Detail

Summary

• Symbol: Btla^tm1Dgra
• Name: B and T lymphocyte associated; targeted mutation 1, Daniel Graf
• MGI ID: MGI:3842627
• Gene: Btla Location: Chr16:45043121-45073258 bp, + strand Genetic Position: Chr16, 29.52 cM
• Alliance: Btla^tm1Dgra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147751
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Part of the promoter and all of exon 1 were removed. Gene inactivation was confirmed by an absence of mRNA detected by Northern blot analysis. (J:147751)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Btla Mutation: 30 strains or lines available

References

• Original: J:147751 Liu X, et al., Cutting edge: A critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction. J Immunol. 2009 Apr 15;182(8):4516-20
• All: 2 reference(s)