Tg(BCL2)#Wehi
Transgene Detail

Summary

• Symbol: Tg(BCL2)#Wehi
• Name: transgene insertion, Walter and Eliza Hall Institute of Medical Research
• MGI ID: MGI:3842923
• Synonyms: Emu-Bcl2
• Transgene: Tg(BCL2)#Wehi Location: unknown
• Alliance: Tg(BCL2)#Wehi page

Transgene origin

• Strain of Origin: (C57BL/6JWehi x SJL/JWehi)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(BCL2)#Wehi expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BCL2 (596)

  Bcl2	(MGI:88138)

• Mutation details: The transgene construct consists of the human BCL2 cDNA in association with the Emu immunoglobulin heavy chain enhancer and SV40 promoter. Three lines were created (lines 22, 25, and 26). The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:93111)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:93111 Strasser A, et al., Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. Curr Top Microbiol Immunol. 1990;166:175-81
• All: 18 reference(s)