Nat3^tm1Dmg
Targeted Allele Detail

Summary

• Symbol: Nat3^tm1Dmg
• Name: N-acetyltransferase 3; targeted mutation 1, Denis M Grant
• MGI ID: MGI:3843196
• Gene: Nat3 Location: Chr8:67976506-68001279 bp, + strand Genetic Position: Chr8, 33.39 cM, cytoband B3.1
• Alliance: Nat3^tm1Dmg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147933
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neo cassette was inserted into the coding sequence at about 480 bp from the start of the 5' UTR. RT-PCR analysis confirmed the absence of expression in homozygous mice. (J:147933)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nat3 Mutation: 17 strains or lines available

References

• Original: J:147933 Sugamori KS, et al., Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse. Drug Metab Dispos. 2007 Jul;35(7):1064-70
• All: 1 reference(s)