Slc3a2^tm1.1Mgin
Targeted Allele Detail

Summary

• Symbol: Slc3a2^tm1.1Mgin
• Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; targeted mutation 1, Mark H Ginsberg
• MGI ID: MGI:3843272
• Synonyms: Slc3a2^f
• Gene: Slc3a2 Location: Chr19:8684931-8700733 bp, - strand Genetic Position: Chr19, 5.44 cM
• Alliance: Slc3a2^tm1.1Mgin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134813
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 1 and 2 were floxed and an frt flanked neo cassette was inserted in intron 2 via homologous recombination. The neo cassette was then removed by Flp mediated recombination. (J:134813)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc3a2 Mutation: 39 strains or lines available

References

• Original: J:134813 Feral CC, et al., CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. J Cell Biol. 2007 Aug 13;178(4):701-11
• All: 11 reference(s)