Tekt3^tm1Zuk
Targeted Allele Detail

Summary

• Symbol: Tekt3^tm1Zuk
• Name: tektin 3; targeted mutation 3, Martin M Matzuk
• MGI ID: MGI:3843699
• Gene: Tekt3 Location: Chr11:62952485-62985786 bp, + strand Genetic Position: Chr11, 38.92 cM, cytoband B2
• Alliance: Tekt3^tm1Zuk page

Structural defects in Tekt3^tm1Zuk/Tekt3^tm1Zuk spermatozoa flagella

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148050
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exon 2 was replaced with an Hprt minigene. The absence of transcript expression was confirmed by northern blot analysis on testes extract. (J:148050)

Generation of the Tekt3^tm1Zuk allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tekt3 Mutation: 25 strains or lines available

References

• Original: J:148050 Roy A, et al., Tektin 3 is required for progressive sperm motility in mice. Mol Reprod Dev. 2009 May;76(5):453-9
• All: 1 reference(s)