Tfb1m^tm1.2Lrsn
Targeted Allele Detail

Summary

• Symbol: Tfb1m^tm1.2Lrsn
• Name: transcription factor B1, mitochondrial; targeted mutation 1.2, Nils-Goran Larsson
• MGI ID: MGI:3844231
• Gene: Tfb1m Location: Chr17:3569531-3608056 bp, - strand Genetic Position: Chr17, 2.01 cM
• Alliance: Tfb1m^tm1.2Lrsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148166
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 3 was removed by germ line, cre mediated recombination. (J:148166)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfb1m Mutation: 18 strains or lines available

References

• Original: J:148166 Metodiev MD, et al., Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome. Cell Metab. 2009 Apr;9(4):386-97
• All: 2 reference(s)