Grik3^tm1Cmul
Targeted Allele Detail

Summary

• Symbol: Grik3^tm1Cmul
• Name: glutamate receptor, ionotropic, kainate 3; targeted mutation 1, Christophe Mulle
• MGI ID: MGI:3844281
• Synonyms: GluR7^-
• Gene: Grik3 Location: Chr4:125384493-125607966 bp, + strand Genetic Position: Chr4, 58.91 cM
• Alliance: Grik3^tm1Cmul page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148310
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A fragment of the gene including the region encoding for the MD2 domain was replaced with a pgk-neo cassette via homologous recombination. (J:148310)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grik3 Mutation: 83 strains or lines available

References

• Original: J:148310 Pinheiro PS, et al., GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12181-6
• All: 6 reference(s)