Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat
Transgene Detail

Summary

• Symbol: Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat
• Name: transgene insertion EH124, GENSAT Project at Rockefeller University
• MGI ID: MGI:3844446
• Synonyms: Founder Line EH124, PKCGluCl-ires-Cre, Tg(Prkcd-EGFP)1Gsat, Tg(Prkcd-EGFP)EH124Gsat, Tg(Prkcd-glc-1/CFP,-cre)1And
• Transgene: Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat Location: unknown
• Alliance: Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat page

Transgene origin

• Strain of Origin: FVB/NTac
• Project Collection: GENSAT

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prkcd (MGI:97598)

• Mutation details: This transgene contains the coding sequence for a chimeric peptide consisting of the alpha subunit of ivermectin-sensitive C. elegans glutamate-gated choride channels (glc-1) and enhanced green fluorescent protein (EGFP) /icre), followed by a polyadenylation signal, an IRES and the cre recombinase gene, inserted into the mouse genomic bacterial artificial chromosome (BAC) RP23-283B12 at the ATG transcription initiation codon of the protein kinase C, delta (Prkcd) gene so that expression of the reporter and recombinase genes is driven by the regulatory sequences of the mouse gene. The GENSAT modified bacterial artificial chromosome (BAC) BX816 was used to generate this transgenic line. (J:100256)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prkcd (mouse) Summary of all recombinase alleles driven by Prkcd. Alliance mouse Prkcd gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:100296 Gong S, et al., A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 2003 Oct 30;425(6961):917-25
• All: 35 reference(s)