Il23r^tm1Kuch
Targeted Allele Detail

Summary

• Symbol: Il23r^tm1Kuch
• Name: interleukin 23 receptor; targeted mutation 1, Vijay K Kuchroo
• MGI ID: MGI:3844602
• Synonyms: IL-23R-eGFP, IL-23R (GFP)
• Gene: Il23r Location: Chr6:67399916-67468839 bp, - strand Genetic Position: Chr6, 30.85 cM
• Alliance: Il23r^tm1Kuch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148248
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An IRES-GFP cassette and a floxed neo cassette were introduced after exon 8 replacing a fragment of the gene including exon 9. (J:148248)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Il23r Mutation: 69 strains or lines available

References

• Original: J:148248 Awasthi A, et al., Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J Immunol. 2009 May 15;182(10):5904-8
• All: 58 reference(s)