Mpz^ttrr
Spontaneous Allele Detail

Summary

• Symbol: Mpz^ttrr
• Name: myelin protein zero; totterer
• MGI ID: MGI:3844951
• Gene: Mpz Location: Chr1:170978282-170988699 bp, + strand Genetic Position: Chr1, 79.05 cM
• Alliance: Mpz^ttrr page

Mutation origin

• Strain of Origin: B6.129P2-Nos3^tm1Unc/J

Mutation description

• Allele Type: Spontaneous
• Mutations: Duplication, Intragenic deletion
• Mutation details: Exon 8 contains a deletion of 4 nucleotides and a duplication of 12 nucleotides, which is predicted to result in multiple amino acid changes at the protein amino terminus. (J:149880)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mpz Mutation: 28 strains or lines available

References

• Original: J:149880 Karst SY, et al., Totterer: a new mutation in the myelin protein Mpz gene. MGI Direct Data Submission. 2009
• All: 1 reference(s)