Ptprz1^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Ptprz1^tm1Vlcg
• Name: protein tyrosine phosphatase receptor type Z, polypeptide 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3845016
• Synonyms: RPTPz^-
• Gene: Ptprz1 Location: Chr6:22875501-23052915 bp, + strand Genetic Position: Chr6, 9.92 cM
• Alliance: Ptprz1^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148388
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 3 though 9 were replaced with a lacZ gene and floxed neo cassette. (J:148388)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprz1 Mutation: 145 strains or lines available

References

• Original: J:148388 Lafont D, et al., A novel role for receptor like protein tyrosine phosphatase zeta in modulation of sensorimotor responses to noxious stimuli: evidences from knockout mice studies. Behav Brain Res. 2009 Jul 19;201(1):29-40
• All: 2 reference(s)