Tg(Ckm-Ppargc1a)31Brsp
Transgene Detail

Summary

• Symbol: Tg(Ckm-Ppargc1a)31Brsp
• Name: transgene insertion 31, Bruce M Spiegelman
• MGI ID: MGI:3845815
• Synonyms: MCK-PGC-1a, mck-PGC-1alpha1, MCK-PGC-1a tg, MPGC-1alpha TG
• Transgene: Tg(Ckm-Ppargc1a)31Brsp Location: unknown
• Alliance: Tg(Ckm-Ppargc1a)31Brsp page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ckm-Ppargc1a)31Brsp expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ppargc1a (MGI:1342774)

• Mutation details: A transgenic construct containing the mouse peroxisome proliferative activated receptor, gamma, coactivator 1 alpha gene under the control of the mouse muscle creatine kinase promoter was injected into fertilized C57BL/6 mouse oocytes. Founder line 31 was subsequently established. (J:78333)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:78333 Lin J, et al., Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 2002 Aug 15;418(6899):797-801
• All: 52 reference(s)