Chi3l1^tm1Eli
Targeted Allele Detail

Summary

• Symbol: Chi3l1^tm1Eli
• Name: chitinase 3 like 1; targeted mutation 1, Jack A Elias
• MGI ID: MGI:3846187
• Synonyms: BRP-39^-, BRP39^-, Chi3l1^-
• Gene: Chi3l1 Location: Chr1:134109894-134117769 bp, + strand Genetic Position: Chr1, 58.15 cM
• Alliance: Chi3l1^tm1Eli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148490
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Intragenic deletion Mutation details: Exons 1-6 and part of the promoter were replaced with a floxed neomycin cassette. Gene inactivation was confirmed by immunoblot analysis of lung extracts. (J:148490)

Generation of the Chi3l1^tm1Eli allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chi3l1 Mutation: 29 strains or lines available

References

• Original: J:148490 Lee CG, et al., Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med. 2009 May 11;206(5):1149-66
• All: 20 reference(s)