Tg(Vil1-Ascl2)1Cle
Transgene Detail

Summary

• Symbol: Tg(Vil1-Ascl2)1Cle
• Name: transgene insertion 1, Hans Clevers
• MGI ID: MGI:3846679
• Synonyms: villin-Ascl2
• Transgene: Tg(Vil1-Ascl2)1Cle Location: unknown
• Alliance: Tg(Vil1-Ascl2)1Cle page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Vil1-Ascl2)1Cle expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ascl2 (MGI:96920)

• Mutation details: Murine Ascl2 coding sequence was put under the control of 9 kb murine Villin promoter. A termination codon and a poly-A sequence from SV40 was included downstream. Transgene expression was detected throughout the intestinal epithelium. (J:148715)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:148715 van der Flier LG, et al., Transcription factor achaete scute-like 2 controls intestinal stem cell fate. Cell. 2009 Mar 6;136(5):903-12
• All: 1 reference(s)