About   Help   FAQ
Vash1tm1Ysat
Targeted Allele Detail
Summary
Symbol: Vash1tm1Ysat
Name: vasohibin 1; targeted mutation 1, Yasufumi Sato
MGI ID: MGI:3846783
Gene: Vash1  Location: Chr12:86725474-86738865 bp, + strand  Genetic Position: Chr12, 40.84 cM
Alliance: Vash1tm1Ysat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148726
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA loxP/FRT flanked neomycin selection cassette replaced 6.6 kb of the locus, including exon 1 that contains the ATG start codon. Gene inactivation was confirmed by a lack of signal in RT-PCR analysis of ear skin. (J:148726)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vash1 Mutation:  20 strains or lines available
References
Original:  J:148726 Kimura H, et al., Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis. Blood. 2009 May 7;113(19):4810-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory