Vash2^tm1Ysat
Targeted Allele Detail

Summary

• Symbol: Vash2^tm1Ysat
• Name: vasohibin 2; targeted mutation 1, Yasufumi Sato
• MGI ID: MGI:3846784
• Synonyms: VASH-2^LacZ
• Gene: Vash2 Location: Chr1:190679843-190711493 bp, - strand Genetic Position: Chr1, 96.28 cM
• Alliance: Vash2^tm1Ysat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148726
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 was replaced with a LacZ/neomycin cassette. Gene inactivation was confirmed by a lack of signal in RT-PCR analysis of ear skin. (J:148726)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vash2 Mutation: 15 strains or lines available

References

• Original: J:148726 Kimura H, et al., Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis. Blood. 2009 May 7;113(19):4810-8
• All: 6 reference(s)