Tsc22d1^tm1Clgr
Targeted Allele Detail

Summary

• Symbol: Tsc22d1^tm1Clgr
• Name: TSC22 domain family, member 1; targeted mutation 1, Michael Caligiuri
• MGI ID: MGI:3847243
• Synonyms: TSC-22^-
• Gene: Tsc22d1 Location: Chr14:76652401-76745205 bp, + strand Genetic Position: Chr14, 40.44 cM
• Alliance: Tsc22d1^tm1Clgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148897
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on bone marrow cells. (J:148897)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsc22d1 Mutation: 90 strains or lines available

References

• Original: J:148897 Yu J, et al., TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. Blood. 2009 May 28;113(22):5558-67
• All: 1 reference(s)