Tg(SMN2*)1951Ahmb
Transgene Detail
|
|
| Symbol: |
Tg(SMN2*)1951Ahmb |
| Name: |
transgene insertion 1951, Arthur H M Burghes |
| MGI ID: |
MGI:3847329 |
| Synonyms: |
line 1951, SMN(VDQNQKE) |
| Transgene: |
Tg(SMN2*)1951Ahmb Location: unknown
|
| Alliance: |
Tg(SMN2*)1951Ahmb page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The transgenic construct encodes a truncated form of SMN2 (exons 1-6) with the added motif VDQNQKE under control of a 4.1 kb SMN2 promoter. Ten founder lines were obtained and lines 1946, 1947, and 1951 (which received more characterization) were established.
(J:148541)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:148541 Workman E, et al., A SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA mice. Hum Mol Genet. 2009 Jun 15;18(12):2215-29 |
| All: |
1 reference(s) |
|
Analysis Tools
