Kcng4^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Kcng4^{tm1(KOMP)Vlcg}
• Name: potassium voltage-gated channel, subfamily G, member 4; targeted mutation 1, Velocigene
• MGI ID: MGI:3847491
• Synonyms: Kcng4^-
• Gene: Kcng4 Location: Chr8:120350593-120362419 bp, - strand Genetic Position: Chr8, 68.07 cM
• Alliance: Kcng4^{tm1(KOMP)Vlcg} page
• IMPC: Kcng4 gene page

Mutation origin

• Mutant Cell Lines: 11043A-A8, 11043A-F4, 11043A-F7, 11043A-F10, 11043A-F12
• Germline Transmission: Earliest citation of germline transmission: J:302033
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 8001bp between positions 120352371-120360371 of Chromosome 8 (Build GRCm39). RT-PCR analysis of testicular tissue confirmed the absence of expression in homozygous mutant males. (J:136110, J:302033)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Kcng4 Mutation: 24 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)