Bmp7^tm1.2Dgra
Targeted Allele Detail

Summary

• Symbol: Bmp7^tm1.2Dgra
• Name: bone morphogenetic protein 7; targeted mutation 1.2, Daniel Graf
• MGI ID: MGI:3847798
• Synonyms: Bmp7^delta
• Gene: Bmp7 Location: Chr2:172709805-172782114 bp, - strand Genetic Position: Chr2, 95.54 cM
• Alliance: Bmp7^tm1.2Dgra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149134
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exon 1. The absence of transcript expression was confirmed by RT-PCR on embryonic RNA. (J:149134)

Expression

In Structures Affected by this Mutation:

34 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp7 Mutation: 37 strains or lines available

References

• Original: J:149134 Zouvelou V, et al., Generation and functional characterization of mice with a conditional BMP7 allele. Int J Dev Biol. 2009;53(4):597-603
• All: 7 reference(s)