Col2a1^Lpk
Chemically induced Allele Detail

Summary

• Symbol: Col2a1^Lpk
• Name: collagen, type II, alpha 1; longpockets
• MGI ID: MGI:3847803
• Gene: Col2a1 Location: Chr15:97873483-97902525 bp, - strand Genetic Position: Chr15, 53.97 cM
• Alliance: Col2a1^Lpk page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: This mutation was discovered by its visible phenotype among F1 progeny of an ENU mutagenized C57BL/6J male mouse. The mutation was mapped to chromosome 15 and shown to be a mutation in the Col2a1 gene causing a Serine to proline change in the amino acid encoded by codon 1386. (J:187141)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

23 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Col2a1 Mutation: 69 strains or lines available

References

• Original: J:148829 Esapa C, Lpk, longpockets, is an ENU induced mutation and results in a short-limbed phenotype: Record for "Lpk". MGI Direct Data Submission. 2009
• All: 2 reference(s)