Prmt1^tm1Rchd
Targeted Allele Detail

Summary

• Symbol: Prmt1^tm1Rchd
• Name: protein arginine N-methyltransferase 1; targeted mutation 1, Stephane Richard
• MGI ID: MGI:3848226
• Synonyms: Prmt1^fl, PRMT^FL
• Gene: Prmt1 Location: Chr7:44626179-44635844 bp, - strand Genetic Position: Chr7, 29.07 cM
• Alliance: Prmt1^tm1Rchd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149155
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and downstream of exon 5. A flp flanked neo cassette was removed by germ line, frt mediated recombination. (J:149155)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prmt1 Mutation: 35 strains or lines available

References

• Original: J:149155 Yu Z, et al., A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation. Mol Cell Biol. 2009 Jun;29(11):2982-96
• All: 14 reference(s)