Dppa4^tm1.1Hjf
Targeted Allele Detail

Summary

• Symbol: Dppa4^tm1.1Hjf
• Name: developmental pluripotency associated 4; targeted mutation 1.1, H J Felhing
• MGI ID: MGI:3848331
• Synonyms: Dppa4^tdRFP
• Gene: Dppa4 Location: Chr16:48104096-48114600 bp, + strand Genetic Position: Chr16, 30.75 cM
• Alliance: Dppa4^tm1.1Hjf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149143
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a tandem RFP (tdRFP) and floxed neo cassette. Germ line, cre mediated recombination removes the neo cassette. (J:149143)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dppa4 Mutation: 33 strains or lines available

References

• Original: J:149143 Madan B, et al., The pluripotency-associated gene Dppa4 is dispensable for embryonic stem cell identity and germ cell development but essential for embryogenesis. Mol Cell Biol. 2009 Jun;29(11):3186-203
• All: 1 reference(s)