Ntng2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ntng2^tm1Lex
• Name: netrin G2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3848334
• Gene: Ntng2 Location: Chr2:29084738-29138111 bp, - strand Genetic Position: Chr2, 19.57 cM, cytoband A3
• Alliance: Ntng2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149048
• Parent Cell Line: Lex-2 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neo cassette. The absence of protein was confirmed by western blot analysis on brain extracts. (J:149048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntng2 Mutation: 34 strains or lines available

References

• Original: J:149048 Zhang W, et al., Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness. Genes Brain Behav. 2008 Jun;7(4):385-92
• All: 1 reference(s)