Prdx4^tm1.1Jufu
Targeted Allele Detail

Summary

• Symbol: Prdx4^tm1.1Jufu
• Name: peroxiredoxin 4; targeted mutation 1.1, Junichi Fujii
• MGI ID: MGI:3848347
• Synonyms: Prx4^-
• Gene: Prdx4 Location: ChrX:154106914-154123750 bp, - strand Genetic Position: ChrX, 72.38 cM
• Alliance: Prdx4^tm1.1Jufu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149074
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination removed exon 1. The absence of protein expression was confirmed by western blot analysis on pancreas, spleen, kidney, large intestine, and testis of male mice. (J:149074)

Expression

In Mice Carrying this Mutation:	27 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx4 Mutation: 9 strains or lines available

References

• Original: J:149074 Iuchi Y, et al., Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress. Biochem J. 2009 Apr 1;419(1):149-58
• All: 8 reference(s)