Nxf2^tm1.2Jw
Targeted Allele Detail

Summary

• Symbol: Nxf2^tm1.2Jw
• Name: nuclear RNA export factor 2; targeted mutation 1.2, Jeremy Wang
• MGI ID: MGI:3848439
• Gene: Nxf2 Location: ChrX:133845275-133865503 bp, - strand Genetic Position: ChrX, 56.31 cM
• Alliance: Nxf2^tm1.2Jw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149228
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination removed exons 3 through 11. The absence of protein expression was confirmed by western blot analysis of testes extracts. (J:149228)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nxf2 Mutation: 4 strains or lines available

References

• Original: J:149228 Pan J, et al., Inactivation of Nxf2 causes defects in male meiosis and age-dependent depletion of spermatogonia. Dev Biol. 2009 Jun 1;330(1):167-74
• All: 2 reference(s)