Zfx^tm1.1Reiz
Targeted Allele Detail

Summary

• Symbol: Zfx^tm1.1Reiz
• Name: zinc finger protein X-linked; targeted mutation 1.1, Boris Reizis
• MGI ID: MGI:3848796
• Synonyms: Zfx^flox
• Gene: Zfx Location: ChrX:93118237-93167308 bp, - strand Genetic Position: ChrX, 41.48 cM, cytoband D
• Alliance: Zfx^tm1.1Reiz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149654
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 10 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 11. Transient flp expression removed the neo cassette leaving exons 10 and 11 floxed. (J:149654)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfx Mutation: 33 strains or lines available

References

• Original: J:149654 Galan-Caridad JM, et al., Zfx controls the self-renewal of embryonic and hematopoietic stem cells. Cell. 2007 Apr 20;129(2):345-57
• All: 4 reference(s)