Tg(CAG-Nog)1Ych
Transgene Detail

Summary

• Symbol: Tg(CAG-Nog)1Ych
• Name: transgene insertion 1, YiPeng Chen
• MGI ID: MGI:3848915
• Synonyms: pMES-Nog
• Transgene: Tg(CAG-Nog)1Ych Location: unknown
• Alliance: Tg(CAG-Nog)1Ych page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Nog)1Ych expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Nog (MGI:104327)

• Mutation details: The coding sequence of Nog was cloned into a vector in front of an IRES-EGFP sequence under control of the chick beta-actin promoter and the CMV immediate-early enhancer. A STOP cassette flanked by loxP sites was inserted between the CAG promoter and the Noggin sequence. Excision of the STOP cassette by cre recombinase permits expression of Noggin. (J:149232)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:149232 Xiong W, et al., Hand2 is required in the epithelium for palatogenesis in mice. Dev Biol. 2009 Jun 1;330(1):131-41
• All: 8 reference(s)