Cdx2^tm1Khk
Targeted Allele Detail

Summary

• Symbol: Cdx2^tm1Khk
• Name: caudal type homeobox 2; targeted mutation 1, Klaus H Kaestner
• MGI ID: MGI:3848929
• Synonyms: Cdx2^loxP
• Gene: Cdx2 Location: Chr5:147237710-147244059 bp, - strand Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
• Alliance: Cdx2^tm1Khk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149479
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. Flp mediated recombination removed the neo cassette leaving exons 2 and 3 floxed. (J:149479)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdx2 Mutation: 22 strains or lines available

References

• Original: J:149479 Gao N, et al., Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell. 2009 Apr;16(4):588-99
• All: 3 reference(s)