Osr2^{tm4(Osr2*)Jian}
Targeted Allele Detail

Summary

• Symbol: Osr2^{tm4(Osr2*)Jian}
• Name: odd-skipped related 2; targeted mutation 4, Rulang Jiang
• MGI ID: MGI:3849034
• Synonyms: Osr2^Osr2Aki
• Gene: Osr2 Location: Chr15:35296244-35303451 bp, + strand Genetic Position: Chr15, 14.46 cM
• Alliance: Osr2^{tm4(Osr2*)Jian} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149458
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 2.6 kb fragment including the entire coding sequence was replaced with a hexameric Myc epitope tag, an Osr2 cDNA, and a floxed neo cassette. The Osr2 cDNA encodes for OSR2A, a five zinc finger repeat containing protein formed by alternative splicing of Osr2. (J:149458)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Osr2 Mutation: 18 strains or lines available

References

• Original: J:149458 Gao Y, et al., Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Dev Biol. 2009 Apr 15;328(2):200-9
• All: 4 reference(s)