Etv5^tm1.1Xsun
Targeted Allele Detail

Summary

• Symbol: Etv5^tm1.1Xsun
• Name: ets variant 5; targeted mutation 1.1, Xin Sun
• MGI ID: MGI:3849047
• Synonyms: Etv5^fl
• Gene: Etv5 Location: Chr16:22200063-22258320 bp, - strand Genetic Position: Chr16, 13.3 cM, cytoband B1
• Alliance: Etv5^tm1.1Xsun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149477
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt flanked neo cassette with a 3' loxP site was inserted upstream of exon 10 and an additional loxP site was inserted downstream of exon 11. Germ line, flp mediated recombination removed the neo cassette leaving exons 10 and 11 floxed. (J:149477)

Expression

In Mice Carrying this Mutation:

4 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Etv5 Mutation: 271 strains or lines available

References

• Original: J:149477 Zhang Z, et al., FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds. Dev Cell. 2009 Apr;16(4):607-13
• All: 16 reference(s)